Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations.

Laura D MathiesFazil Alievnull nullAndrew G DaviesDanielle M Dick Jill C Bettinger

Published in: Alcoholism, clinical and experimental research (2017)

We detected associations between the SWI/SNF complex and AD in an adult population selected from treatment-seeking probands and antisocial behavior in an adolescent population sample. This provides strong support for a role for SWI/SNF in the development of alcohol-related problems.

Keyphrases

mental health
endothelial cells
young adults
gene expression
alcohol consumption
dna damage
transcription factor
induced pluripotent stem cells
genome wide
pluripotent stem cells
dna methylation
combination therapy
replacement therapy
childhood cancer