Compassionate use of esketamine intranasal in patients with severe major depressive disorder resistant to the treatment.

Luis Gutiérrez-RojasJulia Vendrell-SerresJ Antoni Ramos-QuirogaJon Iñaki Etxeandia-PraderaEduardo AguilarAna Isabel De Santiago-DíazDaniel Hernandez-HuertaVicente TorderaCarlos Vázquez-VentosoMoisés BolívarAsunción AbrilRubén Catalán-BarragánJesús García-Jiménez

Published in: Journal of psychopharmacology (Oxford, England) (2024)

ESK-IN has proven to be effective and safe in a clinical sample of patients with severe TRD. To optimize clinical outcomes, the pharmacological treatment for TRD should always be integrated into a comprehensive therapeutic plan that encompasses strategies such as psychotherapy, social support, and family interventions.

Keyphrases

major depressive disorder
social support
bipolar disorder
depressive symptoms
combination therapy
drug induced