Dynamic methylation pattern of H19DMR and KvDMR1 in bovine oocytes and preimplantation embryos.

Carolina Gennari Verruma Renan S Santos Jorge Augusto Petroli Marchesi Sarah Leyenne Alves Sales Reginaldo A Vila Álvaro Fabrício Lopes Rios Cristiana Libardi Miranda Furtado Ester Silveira Ramos

Published in: Journal of assisted reproduction and genetics (2024)

We highlighted the heterogeneity in the DNA methylation of H19DMR and KvDMR1 and a dynamic expression pattern of genes controlled by them. The expression of DNMTs and TETs genes was also dynamic owing to epigenetic reprogramming.

Keyphrases

dna methylation
genome wide
poor prognosis
gene expression
copy number
bioinformatics analysis
single cell
long non coding rna
genome wide identification
transcription factor