Randomized clinical trial and meta-analysis of the impact of a fibrin sealant patch on pancreatic fistula after distal pancreatectomy: CPR trial.
T H MungroopNicky van der HeijdeO R BuschI H de HinghJ J ScheepersM G DijkgraafB Groot KoerkampMarc G H BesselinkC H van EijckPublished in: BJS open (2021)
Application of a fibrin patch to the pancreatic stump does not reduce the incidence of POPF in distal pancreatectomy. Future studies should focus on alternative fistula mitigation strategies, considering pancreatic neck thickness and duct size as risk factors. Trial registration number NL5876 (Netherlands Trial Registry).