Association of Genome-Wide Polygenic Risk Score for Body Mass Index With Cardiometabolic Health From Childhood Through Midlife.

Mengyao Shi Wei Chen Xiao Sun Lydia A Bazzano Jiang He Alexander C Razavi Changwei Li Lu Qi Amit V Khera Tanika N Kelly

Published in: Circulation. Genomic and precision medicine (2022)

Adiposity-related genetic information independently predicted cardiometabolic health in White BHS participants. Null associations observed in Black BHS participants highlight the urgent need for PRS development in multi-ancestry populations.

Keyphrases

genome wide
body mass index
public health
healthcare
health information
mental health
dna methylation
weight gain
copy number
physical activity
insulin resistance
skeletal muscle
social media
human health
risk assessment
genome wide association study