Impacts of three inspiratory muscle training programs on inspiratory muscles strength and endurance among intubated and mechanically ventilated patients with difficult weaning: a multicentre randomised controlled trial.
Thomas RéginaultRoberto Martinez AlejosRoxane CoueronJean-François BurleAlexandre BoyerEric FrisonFrédéric VargasPublished in: Journal of intensive care (2024)
Among difficult-to-wean patients receiving invasive MV, no statistically difference was observed in strength and endurance progression across three different IMT programs. IMT appears to be feasible in usual cares, but some serious adverse events such as bradycardia could motivate further research on the specific impact on cardiac system. Trial registration Clinicaltrials.gov identifier: NCT02855619. Registered 28 September 2014.
Keyphrases
- study protocol
- skeletal muscle
- high intensity
- randomized controlled trial
- public health
- clinical trial
- resistance training
- intensive care unit
- mechanical ventilation
- acute respiratory distress syndrome
- phase iii
- open label
- left ventricular
- double blind
- virtual reality
- body composition
- heart failure
- extracorporeal membrane oxygenation