Protocol for a prospective observational study of adverse drug reactions of anti-epileptic drugs in children in the UK.

Oluwaseun EgunsolaHelen M SammonsShalini OjhaWilliam WhitehouseMark AndersonDan HawcuttImti Choonara

Published in: BMJ paediatrics open (2017)

Toxicity of individual AEDs when given as monotherapy and polytherapy will be determined. Additionally, discontinuation rates due to ADRs will be determined. The data will assist clinicians in choosing AEDs with the least toxicity.

Keyphrases

adverse drug
electronic health record
oxidative stress
young adults
randomized controlled trial
drug induced
emergency department
palliative care
combination therapy
big data
oxide nanoparticles
machine learning
deep learning
artificial intelligence