Human adipose and synovial-derived MSCs synergistically attenuate osteoarthritis by promoting chondrocyte autophagy through FoxO1 signaling.

Jianqun WuSongqiang HuangYangyi YuQiang LianYang LiuWenfeng DaiQisong LiuYonghao PanGui-Ang LiuKai LiChao LiuGuangheng Li

Published in: Stem cell research & therapy (2024)

A combination of human ADSCs and SDSCs demonstrated higher potential than a single type of stem cell, demonstrating potential as a novel treatment for OA.

Keyphrases

endothelial cells
stem cells
signaling pathway
pluripotent stem cells
cell death
knee osteoarthritis
rheumatoid arthritis
transcription factor
adipose tissue
metabolic syndrome
bone marrow
skeletal muscle
replacement therapy
smoking cessation