Trends in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Seroprevalence in Massachusetts Estimated from Newborn Screening Specimens.
Kevin C MaJaime E HaleYonatan H GradGalit AlterKatherine LuzuriagaRoger B EatonStephanie FischingerDevinder KaurRobin BrodySameed M SiddiquiDylan LeachCatherine M BrownR Monina KlevensLawrence MadoffAnne Marie ComeauPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Cumulative incidence of SARS-CoV-2 protective antibody in Massachusetts was low as of December 2020, indicating that a substantial fraction of the population was still susceptible. Maternal seroprevalence data from newborn screening can inform longitudinal trends and identify cities and towns at highest risk, particularly in settings where widespread diagnostic testing is unavailable.