Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311).
Matthew J FerrisYael FlamandGregory S WeinsteinShuli LiHarry QuonRanee MehraJoaquin J GarciaChristine H ChungMaura L GillisonUmamaheswar DuvvuriBert W O'MalleyEnver OzerGiovana R ThomasWayne M KochNeil D GrossRichard B BellNabil F SabaMiriam N LangoEduardo MéndezBarbara A BurtnessPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
Primary TOS and reduced postoperative RT result in outstanding oncologic outcome and favorable functional outcomes in intermediate-risk HPV+ OPC.
Keyphrases
- phase ii
- locally advanced
- radiation therapy
- low dose
- papillary thyroid
- clinical trial
- rectal cancer
- open label
- squamous cell
- phase iii
- squamous cell carcinoma
- minimally invasive
- neoadjuvant chemotherapy
- lymph node metastasis
- patients undergoing
- randomized controlled trial
- study protocol
- high dose
- coronary artery bypass
- high grade
- coronary artery disease
- childhood cancer
- lymph node
- robot assisted
- double blind