Adoptive transfer of dendritic cells expressing CD11c reduces the immunological response associated with experimental colitis in BALB/c mice.
Lisiery N PaiattoFernanda G D SilvaÁureo T YamadaWirla M S C TamashiroPatrícia Ucelli SimioniPublished in: PloS one (2018)
The results allow us to conclude that the adoptive transfer of cells expressing CD11c is able to reduce the clinical and immunological signs of drug-induced colitis. Adoptive transfer of CD11c+DC isolated from both naive and tolerant mice altered the proliferative and T cell responses. To the best of our knowledge, there is no previously published data showing the protective effects of DCs from naïve or tolerant mice in the treatment of colitis.
Keyphrases
- dendritic cells
- cell therapy
- high fat diet induced
- wild type
- induced apoptosis
- healthcare
- immune response
- emergency department
- randomized controlled trial
- cell cycle arrest
- oxidative stress
- hiv infected
- insulin resistance
- systematic review
- machine learning
- mesenchymal stem cells
- big data
- metabolic syndrome
- electronic health record
- regulatory t cells
- ulcerative colitis
- cell death
- cell proliferation
- electron transfer
- skeletal muscle
- pi k akt