The Tuberculosis Sentinel Research Network (TB-SRN) of the International epidemiology Databases to Evaluate AIDS (IeDEA): protocol for a prospective cohort study in Africa, Southeast Asia and Latin America.
Leslie A EnaneStephany N DudaThida ChanyachukulCarolyn Bolton-MooreNeelima NavuluriEugène MessouNana MbonzeLaQuita R McDadeMarina Cruvinel FigueiredoJeremy RossDenise EvansLameck DieroRobert AkpataNatalia ZotovaAimee FreemanMarie Flore PierreDhanushi RupasingheMarie BallifHelen ByakwagaNathalie de CastroMartine TabalaTimothy R SterlingAnnette H SohnLukas FennerKara Wools-KaloustianArmel PodaMarcel YotebiengRobin HuebnerOlivier Marcynull nullPublished in: BMJ open (2024)
Ethics approval was obtained at all implementing study sites, including the Vanderbilt University Medical Center Human Research Protections Programme. Participants will provide informed consent; for minors, this includes both adolescent assent and the consent of their parent or primary caregiver. Protections for vulnerable groups are included, in alignment with local standards and considerations at sites. Procedures for requesting use and analysis of TB-SRN data are publicly available. Findings from TB-SRN analyses will be shared with national TB programmes to inform TB programming and policy, and disseminated at regional and global conferences and other venues.
Keyphrases
- mycobacterium tuberculosis
- public health
- big data
- endothelial cells
- pulmonary tuberculosis
- healthcare
- quality improvement
- mental health
- randomized controlled trial
- young adults
- clinical trial
- electronic health record
- emergency department
- machine learning
- study protocol
- deep learning
- artificial intelligence
- induced pluripotent stem cells
- antiretroviral therapy
- hiv aids
- human immunodeficiency virus