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Circular RNAs arising from synaptic host genes during human neuronal differentiation are modulated by SFPQ RNA-binding protein.

Michelle E WattsMarika OksanenSanna LejerkransFrancesca MastropasquaMyriam GorospeKristiina Tammimies
Published in: BMC biology (2023)
Our study provides an in-depth characterisation of circRNAs in a human neuronal differentiation model and highlights SFPQ as both a regulator and binding partner of circRNAs elevated during neuronal maturation.
Keyphrases
  • endothelial cells
  • binding protein
  • pluripotent stem cells
  • cerebral ischemia
  • genome wide
  • gene expression
  • human immunodeficiency virus
  • subarachnoid hemorrhage
  • dna binding
  • brain injury
  • genome wide analysis