RAMP1 Protects Hepatocytes against Ischemia-reperfusion Injury by Inhibiting the ERK/YAP Pathway.

Yongsheng TangZenan YuanXu LuYingqiu SongShuguang ZhuChunhui QiuQi ZhangBinsheng FuChangchang Jia Hua Li

Published in: Journal of clinical and translational hepatology (2024)

Our findings suggest that RAMP1 protects against HIRI by inhibiting ERK and YAP phosphorylation signal transduction, highlighting its potential as a therapeutic target for HIRI and providing a new avenue for intervention.

Keyphrases

signaling pathway
pi k akt
randomized controlled trial
cell proliferation
liver injury
protein kinase
drug induced