Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery.
Soledad LópezSara García-SerranoCarolina Gutierrez-RepisoFrancisca Rodríguez-PachecoAilec Ho-PlagaroConcepción Santiago-FernandezGonzalo AlbaMarta Cejudo-GuillenAlberto Rodríguez-CañeteSergio ValdesLourdes Garrido-SanchezDavid PozoEduardo Garcia-FuentesPublished in: Obesity surgery (2019)
There is a tissue-specific phenotype and activation of iNKT cells in VAT in morbid obesity, which could be involved in VAT immunometabolism dysregulation. Also, the increase in CD1d expression could be to offset the lack of VAT iNKT cells.