A dynamic time-to-event model for prediction of acute graft-versus-host disease in patients after allogeneic hematopoietic stem cell transplantation.
Katharina OchAmin T TurkiKatharina M GötzDominik SelzerChristian BrossetteStefan TheobaldYvonne BraunNorbert GrafJochen RauchKerstin RohmGabriele WeilerStephan KieferUlf SchwarzLisa EisenbergNico PfeiferMatthias IhleAndrea GrandjeanSonja FixClaudia RiedeJürgen RisslandSigrun SmolaDietrich W BeelenDominic Kaddu-MulindwaJörg BittenbringThorsten LehrPublished in: Cancer medicine (2023)
Overall, the presented model showed good descriptive and predictive performance and provides valuable insights into the interplay of multiple static and time-dependent risk factors for the prediction of aGvHD.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- acute lymphoblastic leukemia
- liver failure
- prognostic factors
- peritoneal dialysis
- patient reported outcomes
- respiratory failure
- patient reported
- acute respiratory distress syndrome