Effects of Home-Based Electrical Stimulation on Plasma Cytokines Profile, Redox Biomarkers, and Metalloproteinases in the Heart Failure with Reduced Ejection Fraction: A Randomized Trial.
Marianne Lucena da SilvaIvo Vieira de Sousa NetoAlexandra C G B de LimaFabrício BarinOtávio Toledo NóbregaRita de Cássia MarquetiGraziella F B CiprianoJoão Luiz Quagliotti DuriganEduardo Antônio FerreiraMartim BottaroRoss ArenaLarry P CahalinJosé Alberto NederWagner Rodrigues MartinsPublished in: Journal of cardiovascular development and disease (2022)
LFES protocol is a promising intervention to modulate MMPs activity in HFrEF patients, although with limited functional effects. These preliminary responses may help the muscle to adapt to future mechanical demands dynamically.