Monocarboxylate transporter 9 (MCT9) is down-regulated in renal cell carcinoma.
Ara YooHyeonhee LeeJinyoung JungSang Seok KohSoojin LeePublished in: Genes & genomics (2021)
MCT9 was identified as a novel highly downregulated gene in renal cell cancer, and its overexpression clearly attenuated RCC cell proliferation. Thus, functional analysis of MCT9 may help in deciphering a yet-undiscovered kidney-specific energy metabolism during renal tumor progression.
Keyphrases
- renal cell carcinoma
- cell proliferation
- papillary thyroid
- transcription factor
- single cell
- poor prognosis
- cell cycle
- squamous cell
- copy number
- squamous cell carcinoma
- stem cells
- pi k akt
- dna methylation
- lymph node metastasis
- bone marrow
- genome wide identification
- signaling pathway
- young adults
- childhood cancer
- genome wide analysis