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Multidisciplinary surgical strategy for dumbbell neuroblastoma: A single-center experience of 32 cases.

Luca PioThomas BlancTimothé de Saint DenisSabine IrtanDominique Valteau-CouanetJean MichonHervé BrisseLouise Galmiche-RollandLuc JoyeuxThierry OdentCaroline HarteChristophe GlorionMichel ZerahSabine Sarnacki
Published in: Pediatric blood & cancer (2019)
Patients with NBL with persistent spinal canal extension of the tumor after neoadjuvant chemotherapy treated at our center had outcomes that compare favorably with the literature. This is likely due to the multidisciplinary approach to optimal surgical strategy and continuous evaluation of the respective risks of tumor progression. Neurological disability results from initial spinal cord compression or the radicular sacrifice required for tumor resection.
Keyphrases
  • neoadjuvant chemotherapy
  • spinal cord
  • locally advanced
  • lymph node
  • systematic review
  • sentinel lymph node
  • multiple sclerosis
  • poor prognosis
  • neuropathic pain
  • early stage
  • human health
  • blood brain barrier