Apolipoprotein E genotype impact on memory and attention in older persons: the moderating role of personality phenotype.

Benjamin P ChapmanRalph H B BenedictFeng LinShumita RoyAntoine PorteinssonKinga SzigetiHoward FederoffMark Mapstone

Published in: International journal of geriatric psychiatry (2017)

Conscientiousness and Neuroticism moderate APOE associations with memory and executive function. As such, they may be useful phenotypic markers in refining the prognostic significance of this polymorphism. Effect-modifying personality traits also provide clues about behavioral and psychological factors that influence the cognitive impact of APOE. Copyright © 2017 John Wiley & Sons, Ltd.

Keyphrases

working memory
cognitive decline
high fat diet
physical activity
high intensity
mild cognitive impairment
social support
community dwelling
type diabetes
metabolic syndrome
adipose tissue
sleep quality