Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.

Alyssa BallKriti KhatriJill GlesnerLisa D VailesSabina WünschmannScott A GabelGeoffrey A MuellerJian ZhangR Stokes PeeblesMartin D ChapmanScott A SmithMaksymilian ChruszczAnna Pomés

Published in: The Journal of allergy and clinical immunology (2024)

These data establish the structural basis of allergenicity of 2 hIgE mAb nonoverlapping epitopes on Der p 2, which appear to make important contributions to the hIgE repertoire against Der p 2 and provide molecular targets for future design of allergy therapeutics.

Keyphrases

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monoclonal antibody
structural basis
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