A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts.
Michel PaquetteSerge PhoenixChristine LawsonBrigitte GuérinRoger LecomteLee-Hwa TaiÉric E TurcotteJeffrey V LeytonPublished in: EJNMMI research (2020)
This protocol can provide high contrast images of tumors expressing ER or HER2 within 3 days from injection of 4FMFES to final scan of 89Zr-T and, hence, provides a basis for future dual-tracer combinations that include antibodies.
Keyphrases
- pet imaging
- positron emission tomography
- computed tomography
- randomized controlled trial
- endoplasmic reticulum
- estrogen receptor
- breast cancer cells
- high resolution
- high throughput
- pet ct
- current status
- optical coherence tomography
- convolutional neural network
- cell therapy
- ultrasound guided
- stem cells
- mesenchymal stem cells
- fluorescence imaging
- photodynamic therapy