In vivo efficacy of WCK 6777 (ertapenem/zidebactam) against carbapenemase-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model.
Matthew GethersIris ChenKamilia AbdelraoufDavid P NicolauPublished in: The Journal of antimicrobial chemotherapy (2022)
Human-simulated exposures of WCK 6777 demonstrated potent in vivo activity against CP-KP, including those with WCK 6777 MICs up to 8 mg/L.