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High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission.

Arnav AgarwalJohn BasmajiFiona MuttalibDavid GrantonDipayan ChaudhuriDevin ChetanMalini HuShannon M FernandoKimia HonarmandLayla BakaaSonia BrarBram RochwergNeill K AdhikariFrancois LamontagneSrinivas MurthyDavid S C HuiCharles GomersallSamira MubarekaJanet V DiazKaren E A BurnsRachel CoubanQuazi IbrahimGordon H GuyattPer Olav Vandvik
Published in: Canadian journal of anaesthesia = Journal canadien d'anesthesie (2020)
High-flow nasal cannula may reduce the need for invasive ventilation and escalation of therapy compared with COT in COVID-19 patients with acute hypoxemic respiratory failure. This benefit must be balanced against the unknown risk of airborne transmission.
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