The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods.

Sarka SalajkovaFilip HavelMichal SramekFilip Novotný David Malinak Rafael DolezalLukas PrchalMarketa Benkova Ondrej Soukup Kamil Musilek Teodorico C RamalhoJiri BartekJan Proska Monika ZarskaZdenek Hodny

Published in: International journal of nanomedicine (2021)

OEG+GNRs appear to be optimal for clinical applications with systemic administration of NPs not-requiring irradiation at high laser intensity such as drug delivery and photothermal therapy inducing apoptosis.

Keyphrases

drug delivery
cancer therapy
drug release
endoplasmic reticulum stress
oxidative stress
cell cycle arrest
photodynamic therapy
high intensity
reduced graphene oxide
high speed
silver nanoparticles
radiation therapy
pi k akt
gold nanoparticles
signaling pathway
oxide nanoparticles