Kamil Musilek

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Venues

Journal of enzyme inhibition and medicinal chemistry

Molecules (Basel, Switzerland)

Archives of toxicology

Medicinal research reviews

University Hospital in Hradec Kralove

Charles University, Faculty of Pharmacy (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Hospital in Hradec Kralove

Czechia

Senior Researcher :: Biomedical Research Centre

University of Hradec Kralove, Faculty of Science

Czechia

Head of Department :: Department of Chemistry

University of Defence, Faculty of Military Health Sciences

Czechia

Academic Position :: Department of Toxicology

Education History

Charles University, Faculty of Pharmacy

Czechia

PHD :: Department of Pharmaceutical Chemistry and Drug Control

Charles University, Faculty of Pharmacy

Czechia

MSC

Publications

Eliska Prchalova, Rudolf Andrys, Jaroslav Pejchal, Zuzana Kohoutova, Karolina Knittelova, Tereza Hofmanova, Adam Skarka, Alzbeta Dlabkova, Miroslav Psotka, Lukas Prchal, Kamil Musilek, Jana Zdarova Karasova, David Malinak
Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents. Archives of toxicology 98 (9) (2024)
Eliska Prchalova, Rudolf Andrys, Jaroslav Pejchal, Zuzana Kohoutova, Karolina Knittelova, Tereza Hofmanova, Adam Skarka, Alzbeta Dlabkova, Miroslav Psotka, Lukas Prchal, Kamil Musilek, Jana Zdarova Karasova, David Malinak
Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents. Archives of toxicology (2024)
Eliska Prchalova, Zuzana Kohoutova, Karolina Knittelova, David Malinak, Kamil Musilek
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system. Archives of toxicology (2023)
Tomáš Roušar, Jiri Handl, Jan Capek, Pavlina Nyvltova, Erika Rousarova, Miroslav Kubat, Lenka Smid, Jana Vanova, David Malinak, Kamil Musilek, Petr Česla
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells. Archives of toxicology (2023)
Monika Schmidt, Michaela Vaskova, Aneta Rotterova, Pavlina Fiandova, Marketa Sedlacek Miskerikova, Lucie Zemanova, Ondrej Benek, Kamil Musilek
Physiologically relevant fluorescent assay for identification of 17β-hydroxysteroid dehydrogenase type 10 inhibitors. Journal of neurochemistry (2023)
Annamaria Haleckova, Ondrej Benek, Lucie Zemanova, Rafael Dolezal, Kamil Musilek
Small-molecule inhibitors of cyclophilin D as potential therapeutics in mitochondria-related diseases. Medicinal research reviews 42 (5) (2022)
Radomir Juza, Kamil Musilek, Eva Mezeiova, Ondrej Soukup, Jan Korabecny
Recent advances in dopamine D 2 receptor ligands in the treatment of neuropsychiatric disorders. Medicinal research reviews 43 (1) (2022)
Zuzana Kohoutova, David Malinak, Rudolf Andrys, Jana Svobodova, Miroslav Psotka, Monika Schmidt, Lukas Prchal, Kamil Musilek
Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides. Journal of enzyme inhibition and medicinal chemistry 37 (1) (2022)
Jiri Handl, David Malinak, Jan Capek, Rudolf Andrys, Erika Rousarova, Martina Hauschke, Lenka Bruckova, Petr Česla, Tomáš Roušar, Kamil Musilek
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening. Chemical research in toxicology 34 (3) (2021)
Radomir Juza, Kristyna Stefkova, Wim Dehaen, Alena Randakova, Tomas Petrasek, Iveta Vojtěchová, Tereza Kobrlova, Lenka Pulkrabkova, Lubica Múčková, Marko Mecava, Lukas Prchal, Eva Mezeiova, Kamil Musilek, Ondrej Soukup, Jan Korabecny
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole. Biomolecules 11 (9) (2021)
Lhassane Ismaili, Julie Monnin, Adeline Etievant, Raquel L Arribas, Lucía Viejo, Bernard Refouvelet, Ondrej Soukup, Jana Janockova, Vendula Hepnarova, Jan Korabecny, Tomas Kucera, Daniel Jun, Rudolf Andrys, Kamil Musilek, Aurelie Baguet, Eva M García-Frutos, Angela De Simone, Vincenza Andrisano, Manuela Bartolini, Cristóbal de Los Ríos, José Marco-Contelles, Emmanuel Haffen
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease. ACS chemical neuroscience 12 (8) (2021)
Harsh Kumar, Kanchan Bhardwaj, Ruchi Sharma, Eugenie Nepovimova, Natália Cruz Martins, Daljeet Singh Dhanjal, Reena Singh, Chirag Chopra, Rachna Verma, Kamel A Abd-Elsalam, Ashwani Tapwal, Kamil Musilek, Dinesh Kumar, Teodorico C Ramalho
Potential Usage of Edible Mushrooms and Their Residues to Retrieve Valuable Supplies for Industrial Applications. Journal of fungi (Basel, Switzerland) 7 (6) (2021)
Kanchan Bhardwaj, Ana Sanches Silva, Maria Atanassova, Rohit Sharma, Eugenie Nepovimova, Kamil Musilek, Ruchi Sharma, Mousa A Alghuthaymi, Daljeet Singh Dhanjal, Marcello Nicoletti, Bechan Sharma, Navneet Kumar Upadhyay, Natália Cruz Martins, Prerna Bhardwaj, Teodorico C Ramalho
Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential. Molecules (Basel, Switzerland) 26 (10) (2021)
Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda
Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase. Biomolecules 11 (2) (2021)
Hyun Myung Lee, Rudolf Andrys, Jakub Jończyk, Kyuneun Kim, Avinash G Vishakantegowda, David Malinak, Adam Skarka, Monika Schmidt, Michaela Vaskova, Kamil Latka, Marek Bajda, Young-Sik Jung, Barbara Malawska, Kamil Musilek
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Patrik Oleksak, Miroslav Psotka, Marketa Vancurova, Olena Sapega, Jana Bieblova, Milan Reinis, David Rysanek, Romana Mikyskova, Katarina Chalupova, David Malinak, Jana Svobodova, Rudolf Andrys, Helena Rehulkova, Vojtech Skopek, Pham Ngoc Lam, Jiri Bartek, Zdenek Hodny, Kamil Musilek
Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition. Journal of enzyme inhibition and medicinal chemistry 36 (1) (2021)
Sarka Salajkova, Filip Havel, Michal Sramek, Filip Novotný, David Malinak, Rafael Dolezal, Lukas Prchal, Marketa Benkova, Ondrej Soukup, Kamil Musilek, Teodorico C Ramalho, Jiri Bartek, Jan Proska, Monika Zarska, Zdenek Hodny
The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods. International journal of nanomedicine 16 (2021)
Radomir Juza, Přemysl Vlček, Eva Mezeiova, Kamil Musilek, Ondrej Soukup, Jan Korabecny
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders. Medicinal research reviews 40 (5) (2020)
Óscar M Bautista-Aguilera, Lhassane Ismaili, Mourad Chioua, Rudolf Andrys, Monika Schmidt, Petr Bzonek, María Ángeles Martínez-Grau, Christopher D Beadle, Tatiana Vetman, Francisco López Muñoz, Isabel Iriepa, Bernard Refouvelet, Kamil Musilek, José Marco-Contelles
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy. International journal of molecular sciences 21 (11) (2020)
Lucie Zemanova, Michaela Vaskova, Monika Schmidt, Jana Roubalova, Annamaria Haleckova, Ondrej Benek, Kamil Musilek
RNase T1 Refolding Assay for Determining Mitochondrial Cyclophilin D Activity: A Novel In Vitro Method Applicable in Drug Research and Discovery. Biochemistry 59 (17) (2020)
David Malinak, Rafael Dolezal, Vendula Hepnarova, Miroslava Hozova, Rudolf Andrys, Petr Bzonek, Veronika Racakova, Jan Korabecny, Lukáš Górecki, Eva Mezeiova, Miroslav Psotka, Daniel Jun, Teodorico C Ramalho, Kamil Musilek
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2020)
Monika Schmidt, Ondrej Benek, Lucie Vinklarova, Martina Hrabinová, Lucie Zemanova, Matej Chribek, Vendula Kralova, Lukas Hroch, Rafael Dolezal, Antonin Lycka, Lukas Prchal, Daniel Jun, Laura Aitken, Frank Gunn-Moore, Teodorico C Ramalho, Kamil Musilek
Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment. International journal of molecular sciences 21 (6) (2020)
Patrik Oleksak, Jozef Gonda, Eugenie Nepovimova, Teodorico C Ramalho, Kamil Musilek
The oxazolomycin family: a review of current knowledge. RSC advances 10 (67) (2020)
Lucie Vinklarova, Monika Schmidt, Ondrej Benek, Teodorico C Ramalho, Frank Gunn-Moore, Kamil Musilek
Friend or enemy? Review of 17β-HSD10 and its role in human health or disease. Journal of neurochemistry 155 (3) (2020)
Irene Pachón-Angona, Bernard Refouvelet, Rudolf Andrýs, Helène Martin, Vincent Luzet, Isabel Iriepa, Ignacio Moraleda, Daniel Diez-Iriepa, María-Jesús Oset-Gasque, José Marco-Contelles, Kamil Musilek, Lhassane Ismaili
Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Joyce Sobreiro Francisco Diz de Almeida, Rafael Dolezal, Ondrej Krejcar, Teodorico C Ramalho, Kamil Musilek, Daniel Jun, Tanos Celmar Costa França
Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS). Toxins 10 (10) (2018)
Tamara Zorbaz, David Malinak, Nikola Maraković, Nikolina Maček Hrvat, Antonio Zandona, Michal Novotny, Adam Skarka, Rudolf Andrys, Marketa Benkova, Ondrej Soukup, Maja Katalinić, Teodorico C Ramalho, Zrinka Kovarik, Kamil Musilek
Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents. Journal of medicinal chemistry 61 (23) (2018)
David Malinak, Eugenie Nepovimova, Daniel Jun, Kamil Musilek, Teodorico C Ramalho
Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study. Molecules (Basel, Switzerland) 23 (9) (2018)
Monika Schmidt, Veronika Hrabcova, Daniel Jun, Kamil Kuca, Kamil Musilek
Vector Control and Insecticidal Resistance in the African Malaria Mosquito Anopheles gambiae. Chemical research in toxicology 31 (7) (2018)
Joyce Sobreiro Francisco Diz de Almeida, Samir Frontino de Almeida Cavalcante, Rafael Dolezal, Teodorico C Ramalho, Kamil Musilek, Daniel Jun, Tanos Celmar Costa França
Molecular modeling studies on the interactions of aflatoxin B1 and its metabolites with the peripheral anionic site of human acetylcholinesterase. Journal of biomolecular structure & dynamics 37 (8) (2018)
Kamil Kuca, Daniel Jun, Lucie Junova, Kamil Musilek, Martina Hrabinová, Jorge Alberto Valle da Silva, Teodorico de Castro Ramalho, Marian Valko, Qinghua Wu, Eugenie Nepovimova, Tanos Celmar Costa França
Synthesis, Biological Evaluation, and Docking Studies of Novel Bisquaternary Aldoxime Reactivators on Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon. Molecules (Basel, Switzerland) 23 (5) (2018)
Ondrej Benek, Lukas Hroch, Laura Aitken, Frank Gunn-Moore, Lucie Vinklarova, Teodorico C Ramalho, Daniel I Perez, Concepción Pérez, Ana Martinez, Zdenek Fisar, Kamil Musilek
1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders. Journal of enzyme inhibition and medicinal chemistry 33 (1) (2018)
Letícia Santos-Garcia, Marco Antônio de Mecenas Filho, Kamil Musilek, Teodorico C Ramalho, Teodorico de Castro Ramalho, Elaine Fontes Ferreira da Cunha
QSAR Study of N-Myristoyltransferase Inhibitors of Antimalarial Agents. Molecules (Basel, Switzerland) 23 (9) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kamil Musilek