Ag(I)-Catalyzed Addition of Cyclopropenones and Nitrones to Access Imides.

Jing-Lei XuHu TianJia-Hao KangWu-Xiang KangWei SunRui SunYa-Min LiMeng Sun

Published in: Organic letters (2020)

An unprecedented Ag-catalyzed addition reaction of cyclopropenones and nitrones to access imides was developed. Sequential C-C bond cleavage, N-O bond cleavage, and Mumm rearrangement were uncovered in this process. This protocol exhibited high efficiency, regioselectivity, good yields, and a broad tolerance of various functional groups.

Keyphrases

high efficiency
room temperature
quantum dots
dna binding
highly efficient
randomized controlled trial
visible light
electron transfer
transition metal
transcription factor
ionic liquid