Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure.

Malin LarssonNils RudqvistJohan K E SpetzEmman ShubbarToshima Z ParrisBritta LangenKhalil HelouEva Forssell-Aronsson

Published in: PloS one (2020)

Exposure-related and dose-related effects on gene and protein expression generated few expression patterns useful as biomarkers for thyroid function and cancer.

Keyphrases

low dose
poor prognosis
papillary thyroid
oxidative stress
high dose
squamous cell carcinoma
genome wide
drug induced