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Hepatic nuclear factor 4 alpha promotes the ferroptosis of lung adenocarcinoma via transcriptional activation of cytochrome P450 oxidoreductase.

Valeria BesskayaHuan ZhangYunyi BianJiaqi LiangGuoshu BiGuangyao ShanCheng ZhanZongwu Lin
Published in: PeerJ (2023)
HNF4A promotes POR expression through binding to the POR's promoter, and subsequently promotes the ferroptosis of lung adenocarcinoma.
Keyphrases
  • nuclear factor
  • toll like receptor
  • cell death
  • transcription factor
  • poor prognosis
  • dna methylation
  • binding protein
  • long non coding rna
  • oxidative stress
  • heat shock
  • heat stress