Considering the methodological limitations in the evidence base of antidepressants for depression: a reanalysis of a network meta-analysis.

Klaus MunkholmAsger Sand Paludan-MüllerKim Boesen

Published in: BMJ open (2019)

The evidence does not support definitive conclusions regarding the benefits of antidepressants for depression in adults. It is unclear whether antidepressants are more efficacious than placebo.

Keyphrases

major depressive disorder
depressive symptoms
sleep quality
bipolar disorder
randomized controlled trial
clinical trial
radiation therapy
study protocol
rectal cancer