ZNF703 is an important player in head and neck cancer.

Ceren OrhanBurak BakırNejat DalayNur Buyru

Published in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2019)

ZNF703 over-expression is associated with copy number variation and this over-expression may activate PI3K/Akt signalling pathway in HNSCC.

Keyphrases

copy number
pi k akt
poor prognosis
mitochondrial dna
signaling pathway
cell proliferation
cell cycle arrest
genome wide
binding protein
dna methylation
gene expression
long non coding rna
cell death