Silymarin and celecoxib ameliorate experimental varicocele-induced pathogenesis: evidences for oxidative stress and inflammation inhibition.

Sara MazhariMazdak RaziRajabali Sadrkhanlou

Published in: International urology and nephrology (2018)

The SMN by up-regulating testicular TAC, SOD, GSH-px and TTM levels and the CEL by inhibiting COX2 and iNos expression as well as NO content could fairly ameliorate the VCL-decreased spermatogenesis.

Keyphrases

oxidative stress
diabetic rats
poor prognosis
high glucose
dna damage
ischemia reperfusion injury
signaling pathway
induced apoptosis
drug induced
binding protein
endothelial cells
long non coding rna