Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice.

Jing ZengXinyu MengPing ZhouZhihua YinQinglian XieHong ZouNan ShenZhizhong YeYuanjia Tang

Published in: Arthritis research & therapy (2019)

Our research verified that IFN-α plays a critical role in NP-SLE and provides a comprehensive NP-SLE mouse model for dissecting the mechanisms of NP-SLE and developing novel therapies for intervention.

Keyphrases

systemic lupus erythematosus
disease activity
mouse model
dendritic cells
rheumatoid arthritis
randomized controlled trial
immune response
metabolic syndrome