ACTA2 expression predicts survival and is associated with response to immune checkpoint inhibitors in gastric cancer.

Sunho Park John D Karalis Changjin Hong Jean R Clemenceau Matthew R Porembka In-Ho Kim Sung Hak Lee Sam C Wang Jae Ho Cheong Tae Hyun Hwang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

ACTA2 expression is associated with survival and ICI response in gastric cancer patients. ACTA2 expression in cancer-associated fibroblasts, but not in other cellular compartments, appears to be associated with ICI response.

Keyphrases

poor prognosis
binding protein