Amyloid-like substance in mice and human oocytes and embryos.

Ricardo N PimentelPaula A NavarroFang WangLeRoy G RobinsonMichael CammerFengxia LiangYael KramerDavid Lawrence Keefe

Published in: Journal of assisted reproduction and genetics (2019)

We demonstrate for the first time the presence, distribution, and change in ALS throughout some stages of mouse and human oocyte maturation and embryonic development. We also determine associations between ALS in human oocytes with clinical characteristics.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
type diabetes
adipose tissue
metabolic syndrome
amyotrophic lateral sclerosis
insulin resistance