Left bundle branch area pacing for heart failure patients requiring cardiac resynchronization therapy: A meta-analysis.
Chengyue JinQiying DaiPengyang LiPatrick LamYong Mei ChaPublished in: Journal of cardiovascular electrophysiology (2023)
This meta-analysis of primarily nonrandomized studies suggests that LBBP is associated with a greater improvement in left ventricular systolic function and a lower rate of HFH compared to BVP. There was uniformity of these findings in all of the included studies. However, it would be premature to conclude based solely on the current meta-analysis alone, given the limitations stated. Dedicated, well-designed, randomized controlled trials and observational studies are needed to elucidate better the comparative long-term efficacy and safety of LBBP CRT versus BIV CRT.
Keyphrases
- cardiac resynchronization therapy
- left ventricular
- case control
- systematic review
- heart failure
- meta analyses
- hypertrophic cardiomyopathy
- acute myocardial infarction
- mitral valve
- left atrial
- randomized controlled trial
- aortic stenosis
- clinical trial
- blood pressure
- ejection fraction
- atrial fibrillation
- transcatheter aortic valve replacement
- aortic valve