Final 192-Week Efficacy and Safety Results of the ADVANCE Trial, Comparing 3 First-line Antiretroviral Regimens.
Simiso Mandisa SokhelaWillem Daniel Francois VenterBronwyn BoschJoana WoodsKaitlyn McCannGodspower AkpomiemieNomathemba ChandiwanaNkuli MashabaneAngela TemboBryony SimmonsSamanta Lalla-EdwardMark J SiednerPhumla SinxadiLucas HermansLee FairlieAlinda VosElaine AbramsJennifer M Manne-GoehlerMichelle MoorhousePolly ClaydenShane NorrisAmbar QaviMatthew ChersichMasebole MasenyaNatasha ArulappanAndrew HillPublished in: Open forum infectious diseases (2024)
High viral suppression was seen across arms, with no resistance to DTG. Weight gain continued but slowed after 96 weeks, with few clinical events or laboratory changes.