Predictive potential of various plasma inflammation-, angiogenesis-, and extracellular matrix remodeling-associated mediators for intra-amniotic inflammation and/or microbial invasion of the amniotic cavity in preterm labor.

Eunwook JooSubeen HongKyo Hoon ParkHyeon Ji KimMin Jung LeeSue Shin

Published in: Archives of gynecology and obstetrics (2024)

IGFBP-2, LBP, MMP-2, MMP-8, and S100A8/A9 may represent valuable plasma biomarkers for predicting IAI/MIAC in women with PTL. Combination of LBP, MMP-2, and MMP-8 expression data can significantly improve the predictive potential for IAI/MIAC.

Keyphrases

cell migration
extracellular matrix
oxidative stress
poor prognosis
microbial community
endothelial cells
electronic health record
vascular endothelial growth factor
preterm birth
wound healing