Coinfection with Pseudomonas aeruginosa and Aspergillus fumigatus in cystic fibrosis.
Karen KeownAlastair ReidJohn E MooreClifford C TaggartDamian G DowneyPublished in: European respiratory review : an official journal of the European Respiratory Society (2020)
A complex bi-directional relationship exists between P. aeruginosa and A. fumigatus, exhibiting both mutually antagonistic and cooperative facets. Cross-sectional data indicate a worsened disease state in coinfected patients; however, robust longitudinal studies are required to derive causality and to determine whether interspecies interaction contributes to disease progression.