3'UTR enhances hCD47 cell surface expression, self-signal function, and reduces ER stress in porcine fibroblasts.

Nora HosnyAnders W MatsonRamesh KumbhaMagie SteinhoffJoseph Sushil RaoTaghrid B El-AbaseriNagwan A SabekMoushira A MahmoudBernhard J HeringChristopher Burlak

Published in: Xenotransplantation (2020)

Our results suggest the potential benefits of using hCD47 constructs containing the 3'UTR to generate genetically engineered hCD47-expressing donor pigs.

Keyphrases

cell surface
poor prognosis
binding protein
human health
risk assessment
long non coding rna
climate change