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Adjunctive use of metronidazole-minocycline ointment in the nonsurgical treatment of peri-implantitis: A multicenter randomized controlled trial.

Seung-Hyun ParkYoung Woo SongJae-Kook ChaJung-Seok LeeYoung-Taek KimHyun-Seung ShinDong-Won LeeJae Hyun LeeChang-Sung Kim
Published in: Clinical implant dentistry and related research (2021)
Additive use of either MM or MC results in significantly higher treatment success rates compared to sole mechanical debridement in nonsurgical treatment of peri-implantitis. Moreover, MM contributes to a significantly greater reduction in the PPD compared to MC in deep pockets (cris.nih.go.kr KCT0004557).
Keyphrases
  • randomized controlled trial
  • systematic review
  • study protocol
  • combination therapy