Ultrasound Assessment of Disease Activity Prevents Disease-Modifying Antirheumatic Drug (DMARD) Escalation and May Reduce DMARD-Related Direct Costs in Rheumatoid Arthritis With Fibromyalgia: An Exploratory Study.
Rafael Mendonça da Silva ChakrJoão Cláudio de Oliveira SantosLaura da Silva AlvesNicole Pamplona Bueno de AndradeAline RanzolinClaiton Viegas BrenolPublished in: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine (2020)
In this real-life study of patients with RA and FM, a US examination was associated with less DMARD escalation and could reduce biologic DMARD direct costs. Specifically, synovitis as scored by power Doppler US could be useful as a treatment target for RA in patients with DAS28 overestimation due to FM, but further studies are necessary.
Keyphrases
- disease activity
- rheumatoid arthritis
- rheumatoid arthritis patients
- ankylosing spondylitis
- systemic lupus erythematosus
- juvenile idiopathic arthritis
- interstitial lung disease
- open label
- magnetic resonance imaging
- emergency department
- clinical trial
- mouse model
- blood flow
- combination therapy
- drug induced
- systemic sclerosis
- electronic health record