Association between Metformin Use and Risk of Total Knee Arthroplasty and Degree of Knee Pain in Knee Osteoarthritis Patients with Diabetes and/or Obesity: A Retrospective Study.
Shibo ChenGuangfeng RuanMuhui ZengTianyu ChenPeihua CaoYan ZhangJia LiXiaoshuai WangShengfa LiSu'an TangShilong LuTianxiang FanYang LiWeiyu HanJianye TanChanghai DingZhaohua ZhuPublished in: Journal of clinical medicine (2022)
MET can be a potential therapeutic option for OA. Further clinical trials are needed to determine if MET can reduce the risk of TKA and the severity of knee pain in metabolic-associated OA patients.
Keyphrases
- knee osteoarthritis
- total knee arthroplasty
- chronic pain
- clinical trial
- total hip
- end stage renal disease
- pain management
- ejection fraction
- newly diagnosed
- neuropathic pain
- metabolic syndrome
- type diabetes
- chronic kidney disease
- insulin resistance
- weight loss
- randomized controlled trial
- peritoneal dialysis
- prognostic factors
- physical activity
- spinal cord injury
- skeletal muscle
- anterior cruciate ligament
- patient reported