GDE2 expression in oligodendroglia regulates the pace of oligodendrocyte maturation.
Bo-Ran ChoiMateusz DobrowolskiShanthini SockanathanPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
These studies reveal that oligodendroglial GDE2 expression is required for controlling the pace of oligodendrocyte maturation. Thus, the cell-type specific expression of GDE2 is important for the coordination of oligodendrocyte maturation and axonal myelination during neural development.