Pharmacokinetics, pharmacodynamics and safety studies on URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats.
Valentina VozellaFaizy AhmedPaoula ChoobchianCollin B MerrillCristina ZibardiGiorgio TarziaMarco MorAndrea DurantiAndrea TontiniSilvia RivaraDaniele PiomelliPublished in: The Journal of pharmacy and pharmacology (2019)
Pain remains a major unmet medical need. The favourable pharmacokinetic and pharmacodynamic properties of URB937, along with its tolerability, encourage further development studies on this compound.