Cranial MRI Abnormalities and Long-term Follow-up of the Lesions in 770 Girls With Central Precocious Puberty.
Didem HelvacıoğluSerap Demircioğlu TuranTülay GüranZeynep AtayAdnan DağçınarDiğdem BezenEsin Karakılıç ÖzturanFeyza DarendelilerAyşegül YükselFatma DursunSuna KılınçSerap SemizSaygın AbalıMetin YıldızAşan ÖnderAbdullah BereketPublished in: The Journal of clinical endocrinology and metabolism (2021)
Although age and LH/FSH ratio are significant predictors of CNS lesions, their predictive power is weak. Thus, systematic MRI seems to be the most efficient current approach to avoid missing an occult CNS lesion in girls with CPP, despite the low likelihood of finding a lesion requiring intervention.