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Re-analysis of the coral Acropora digitifera transcriptome reveals a complex lncRNAs-mRNAs interaction network implicated in Symbiodinium infection.

Chen HuangDongliang LengShixue SunXiaohua Douglas Zhang
Published in: BMC genomics (2019)
Our study not only refined A. digitifera transcriptome via identification of novel transcripts and isoforms, but also predicted a high-confidence dataset of lncRNAs. Functional study based on the construction of lncRNAs-mRNAs co-expression network has disclosed a complex lncRNA-mediated regulation in response to Symbiodinium infection exhibited in A. digitifera. Once validated, these lncRNAs could be good potential targets for treatment and prevention of bleaching in coral.
Keyphrases
  • network analysis
  • genome wide analysis
  • gene expression
  • rna seq
  • single cell
  • poor prognosis
  • hydrogen peroxide
  • genome wide identification
  • nitric oxide
  • transcription factor
  • human health