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Sodium L-Aspartate Supplementation Improves Repeated-Sprint Performance.

Keiichi YamaguchiNanako HayashiDaichi SumiMiho OnoTomonori KoizumiWataru SatoFumika TakeuchiYusuke AdachiKazushige Goto
Published in: Nutrients (2023)
Aspartate supplementation has been reported to improve endurance performance by facilitating the tricarboxylic acid cycle flux. The present study was performed to investigate the effects of aspartate supplementation on repeated-sprint performance and blood pH. Following an overnight fast, fourteen healthy males completed three sets of 10 × 6 s maximal sprints after consuming sodium L-aspartate (ASP) or placebo (PLA), in a double-blind manner. Both supplements were taken twice on each test day (2 × 4.5 g). Exercise performance (e.g., cadence and power output) and blood variables (e.g., pH and plasma amino acid levels) were measured. The ASP trial evidenced significantly higher plasma aspartate concentration during the first (ASP, 45.3 ± 9.2 μM; PLA, 6.1 ± 0.8 μM) and the second exercise sets (ASP, 24.2 ± 4.5 μM; PLA, 6.6 ± 0.9 μM) and peak cadence during the second set (ASP, 153 ± 3 rpm; PLA, 152 ± 3 rpm) compared with the PLA trial (all p < 0.05). The peak power output during the second exercise set (ASP, 743 ± 32 W; PLA, 734 ± 31 W; p = 0.060) and the blood pH immediately before (ASP, 7.280 ± 0.020; PLA, 7.248 ± 0.016; p = 0.087) and after the third exercise set (ASP, 7.274 ± 0.019; PLA, 7.242 ± 0.018; p = 0.093) tended to be higher in the ASP than in the PLA trial. In conclusion, ASP supplementation partially improved repeated-sprint performance (peak cadence during the second exercise set). However, it did not affect the mean power output.
Keyphrases
  • high intensity
  • resistance training
  • physical activity
  • phase iii
  • clinical trial
  • study protocol
  • body composition
  • phase ii
  • randomized controlled trial
  • amino acid
  • skeletal muscle
  • heart rate
  • open label