Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections.
Claudia FredoliniTea Dodig-CrnkovićAnnika BendesLeo DahlMatilda DaleVincent AlbrechtCecilia MattssonCecilia Engel ThomasÅsa Torinsson NaluaiMagnus GisslenOlof BeckNiclas RoxhedJochen M SchwenkPublished in: Communications medicine (2024)
Proteome analysis of volumetric self-sampled DBS facilitates precise analysis of clinically relevant proteins, including those secreted into the circulation or found on blood cells, augmenting previous COVID-19 reports with clinical blood collections. Our population surveys support the usefulness of DBS, underscoring the role of timing the sample collection to complement clinical and precision health monitoring initiatives.
Keyphrases
- sars cov
- healthcare
- deep brain stimulation
- coronavirus disease
- induced apoptosis
- public health
- respiratory syndrome coronavirus
- cell cycle arrest
- emergency department
- quality improvement
- cross sectional
- risk assessment
- endoplasmic reticulum stress
- health information
- single cell
- cell death
- cell proliferation
- signaling pathway