Isomalto-oligosaccharides ameliorate visceral hyperalgesia with repair damage of ileal epithelial ultrastructure in rats.

Wei-da WangHaiwei XinXiucai FangHongtao DouFangyi LiuDan HuangShaomei HanGuijun FeiLiming ZhuShenghua ZhaHong ZhangMeiyun Ke

Published in: PloS one (2017)

In this randomized placebo-controlled study, the results showed that IMO ameliorated WAS-induced visceral hyperalgesia in rats, this effect may be attributed to the repair of damages on intestinal epithelial ultrastructure.

Keyphrases

double blind
neuropathic pain
insulin resistance
placebo controlled
open label
high glucose
oxidative stress
diabetic rats
phase iii
clinical trial
adipose tissue
electron microscopy
spinal cord injury
randomized controlled trial
drug induced
spinal cord
skeletal muscle